| Sirius Games |
| Sixteen Tons Entertainment |
| Ska Studios |
| SkyFallen Entertainment |
| Slant Six Games |
| Slapdash |
| Sledgehammer Games |
| Slick Entertainment |
| Slightly Mad Studios |
| Slitherine |
| Smart Bomb Interactive |
| SmartCell Technology |
| Smilebit |
| Snail Games |
| Sniper Studios |
| SNK Playmore |
| Snowberry Connection |
| Snowbird Game Studios |
| Snowblind Studios |
| Soldak Entertainment |
| Sonalysts |
| Sonic Powered Co. |
| Sonic Team |
| Sony Bend |
| Sony Computer Entertainment |
| Sony Online Entertainment |
| Sora Ltd. |
| SouthEnd Interactive |
| SouthPeak Interactive |
| souvenir circ. |
| Spark Unlimited |
| SpellBound |
| Spicy Horse |
| SpiderMonk |
| Spiderweb Software |
| Spike |
| Splash Damage |
| Spline |
| Sports Interactive |
| Sproing |
| Sprout Games |
| Square Enix |
| Stainless Games |
| Stainless Steel Studios |
| Starbreeze Studios |
| Stardock |
| Steel Monkeys |
| Sting |
| Stormfront Studios |
| Stormregion |
| Strange Flavour |
| Strategy First |
| Strawdog Studios |
| Streko-Graphics |
| Studio Gigante |
| Studio Liverpool |
| Studio MDHR |
| Success |
| Sucker Punch |
| Sumo Digital |
